If you are taking an oral contraceptive, we usually recommend you stop taking it. This is mainly because oral contraceptives are known to trigger melasma or worsen existing melasma. On top of that, a combination of tranexamic acid with an oral contraceptive can increase your risk to get a clot in your legs or lungs.

If you have someone in your family who had a clot in his or her legs or lungs, you are very likely not a good candidate for treatment with tranexamic acid. This is because some people get clots more easily than others if they have a family member who had this problem. If you then take tranexamic acid, it could increase your risk more to get a leg clot (Deep Venous Thrombus) or clot in the lungs (Pulmonary Embolism).

You also can not take tranexamic acid if you are pregnant, breastfeeding or have just given birth.