Woman in her forties with visible facial pigmentation, representing doctor-supervised Kligman Solution treatment at Satini Cosmetic Clinic
A personalised prescription plan for clearer, more even-looking skin.

Kligman Solution · Ferrymead, Christchurch

Prescription Kligman Solution for melasma

Melasma can be stubborn. It can fade, then return with sun, hormones, heat or inflammation. Kligman Solution is a prescription topical treatment that targets several causes of excess pigment at the same time.

At Satini Cosmetic Clinic, your formula is prescribed and monitored by a doctor. Our customised version combines hydroquinone, tretinoin and low-concentration dexamethasone. We also add kojic acid to strengthen pigment control.

Doctor prescribedMedical assessment first
Gold standard approachTriple-combination therapy
Custom compoundedKojic acid added at Satini
Ongoing supportReviews and maintenance

What improvement may look like

Clearer, more even-looking skin

Kligman Solution works gradually. You may notice dark patches soften and your overall tone look more even when you use the formula consistently and protect your skin every day.

View Satini results
Illustrative images: These are digitally created examples, not photographs of Kligman patients. Results vary. Your doctor will explain what is realistic for your skin.

What is Kligman Solution?

A four-part prescription approach to melasma

Kligman’s formula is a well-established prescription treatment for melasma. It combines ingredients that slow pigment production, improve skin turnover and reduce inflammation.

The traditional formula contains hydroquinone, tretinoin and dexamethasone. At Satini Cosmetic Clinic, we add kojic acid for extra pigment control. Your formula is compounded for you and supplied only after a doctor has assessed your skin.

Why it is called the Gold Standard: Medical reviews continue to describe the combination of hydroquinone, tretinoin and a topical corticosteroid as the leading topical treatment for melasma.

Kligman Solution may help you with:

  • Melasma
  • Hormonal pigmentation
  • Pregnancy-related pigment after pregnancy
  • Recurring brown facial patches
  • Post-inflammatory pigmentation
  • Uneven dark spots
  • Stubborn pigment after other skincare
  • Maintenance after a professional pigment programme
Prescription onlyDoctor monitoredCustom compoundedHome treatment

What is inside your formula?

Four ingredients. Four complementary actions.

Each ingredient has a different role. Together, they target pigment more effectively than a single brightening ingredient alone.

01

Hydroquinone

The main pigment-reducing ingredient. It blocks tyrosinase, an enzyme your skin uses to produce melanin. This helps existing dark patches fade and slows new pigment formation.

02

Tretinoin

A prescription form of vitamin A. It speeds up skin-cell turnover and helps the other ingredients work more effectively. It can cause dryness or irritation, so your routine is introduced gradually.

03

Dexamethasone

A low-concentration corticosteroid used to calm inflammation and reduce irritation from the active ingredients. It must be used for the prescribed time because prolonged steroid use can thin or sensitise facial skin.

04

Kojic acid

At Satini, we add kojic acid to enhance pigment control. Kojic acid also reduces tyrosinase activity and can support a brighter, more even complexion.

Your treatment journey

How Kligman Solution works at Satini

This is not an over-the-counter fading cream. You receive a medical plan, clear instructions and follow-up.

Doctor consultation

We confirm that the pigment is melasma or another suitable condition. We review your skin type, triggers, medicines, pregnancy plans and current skincare.

Prescription

Your doctor prescribes a compounded formula with hydroquinone, tretinoin, dexamethasone and added kojic acid. The exact plan is chosen for your skin.

Slow introduction

You begin with small amounts and a lower frequency. We increase use only when your skin is comfortable. This helps reduce irritation.

Medical review

We assess your response, check for irritation and adjust the plan. Hydroquinone and steroid-containing formulas should not be used continuously without review.

Maintenance

Once your pigment improves, we may reduce the formula, use it intermittently or change you to non-hydroquinone maintenance products and daily SPF.

Combination treatment

Kligman Solution and tranexamic acid

Melasma has several drivers. For some people, topical treatment alone is not enough. Your doctor may combine Kligman Solution with tranexamic acid as a topical product or a tablet.

Tranexamic acid works through a different pathway. It reduces signals linked with pigment production and the vascular component of melasma. The combination may be useful when your melasma is resistant, recurrent or strongly influenced by hormones.

Important: Oral tranexamic acid is an off-label treatment for melasma. It is not suitable for everyone. Your doctor must assess clotting risks, medical history, medicines and other contraindications before prescribing it.

Your doctor may consider tranexamic acid when:

  • Your melasma keeps returning
  • Your pigment has a strong hormonal pattern
  • Topical treatment has only partly helped
  • You have widespread facial melasma
  • You can safely use oral or topical tranexamic acid
  • You are committed to daily light protection

Oral treatment requires individual medical screening. Topical tranexamic acid may be an option when tablets are unsuitable.

What to expect

Results, irritation and recovery

01

Early adjustment

You may notice dryness, mild peeling, redness or stinging when you begin. Starting slowly and using the right moisturiser can make the treatment easier to tolerate.

02

Gradual improvement

You may begin to see a brighter, more even tone over several weeks. Stubborn or long-standing melasma often needs a longer, carefully monitored plan.

03

Long-term control

Melasma is a chronic condition. Your result is easier to maintain when you use SPF 50+, protect against visible light and follow your maintenance plan.

Use only as prescribed. Overuse can cause irritation, rebound pigmentation, steroid-related skin thinning or, very rarely, ochronosis from prolonged hydroquinone use. Contact Satini if your skin becomes very sore, swollen, blistered or unusually dark.

Compare your options

Kligman Solution, Cosmelan, Dermamelan or IPL?

The best treatment depends on the cause and depth of your pigment, your skin type, your tolerance for downtime and your medical history.

QuestionKligman SolutionCosmelanDermamelanIPL
Often best forMelasma, hormonal pigmentation and recurring diffuse dark patches.Melasma, sun damage and uneven tone needing an intensive clinic and home programme.More resistant melasma or pigmentation needing a stronger medical programme.Discrete sunspots, redness and suitable surface pigment.
FormatCustom-compounded prescription topical treatment used at home.Professional mask plus several months of home care.Prescription in-clinic mask plus an intensive home programme.Light-based treatment performed in clinic.
DowntimeUsually little visible downtime, but dryness, irritation and peeling can occur.Several days of redness, dryness and peeling.Several days of redness and peeling; intensity varies.Mild redness; spots may darken before fading.
Medical oversightEssential. Contains prescription medicines and must be reviewed.Doctor-led at Satini with structured home care.Prescription-only and medically supervised.Suitability must be assessed, especially when melasma is present.
Learn moreHydroquinone and melasmaCosmelan ChristchurchDermamelan ChristchurchIPL facial rejuvenation

IPL is generally not our first choice for melasma because heat and inflammation can trigger recurrence in some skin types.

Why choose Satini?

Prescription pigment care with a doctor

Kligman Solution contains powerful prescription ingredients. It works best when your diagnosis is correct, the formula suits your skin and the treatment is reviewed at the right time.

At Satini Cosmetic Clinic, an experienced cosmetic doctor oversees your treatment from consultation through maintenance. You receive honest guidance about what the formula can achieve and when a different option may be better.

Learn more about Satini Cosmetic Clinic or view our treatment pricing and payment options.

Your plan includes:

  • Doctor consultation and diagnosis
  • Review of triggers and medical history
  • Custom-compounded prescription
  • Clear introduction schedule
  • Skincare and sunscreen guidance
  • Follow-up and formula adjustment
  • Maintenance planning
  • Alternative treatment options when needed

Helpful internal resources

Learn more about melasma and pigmentation

Frequently asked questions

Questions about Kligman Solution

What is Kligman Solution?

It is a prescription topical treatment for melasma. The traditional formula combines hydroquinone, tretinoin and dexamethasone. At Satini, we also add kojic acid to strengthen pigment control.

Why is Kligman Solution called the Gold Standard for melasma?

It treats pigment through several pathways at once. Hydroquinone reduces melanin production, tretinoin improves skin turnover and the corticosteroid reduces inflammation. Medical reviews continue to describe this triple combination as the leading topical treatment for melasma.

Is Kligman Solution prescription only?

Yes. It contains prescription-strength hydroquinone, tretinoin and a corticosteroid. A doctor must confirm that it is suitable, prescribe it and review how your skin responds.

How do I use it?

Your doctor gives you a personalised schedule. You usually begin with a very small amount and use it less often at first. The frequency can increase if your skin tolerates it. Do not copy another person’s routine.

How quickly will I see results?

You may notice early improvement over several weeks. More stubborn melasma can take longer. Your result depends on pigment depth, triggers, skin type, consistency and light protection.

Can I use Kligman Solution long term?

Not continuously without medical review. Hydroquinone and corticosteroids need planned breaks or intermittent use. Once your pigment improves, your doctor may change you to a safer long-term maintenance routine.

Can I combine it with tranexamic acid?

Sometimes. Your doctor may add topical or oral tranexamic acid when melasma is resistant or recurrent. Oral tranexamic acid needs a careful medical and clotting-risk assessment and is not suitable for everyone.

Can I use Kligman Solution during pregnancy?

No. Tretinoin and hydroquinone are generally avoided during pregnancy, and your treatment must be reviewed if you are pregnant, breastfeeding or planning a pregnancy.

Will my melasma come back?

It can. Melasma is often triggered by UV light, visible light, heat and hormones. Daily SPF 50+, hats, trigger control and maintenance skincare help you protect your improvement.

Is Kligman Solution better than Cosmelan or Dermamelan?

It is different rather than universally better. Kligman is a prescription home treatment. Cosmelan and Dermamelan combine an in-clinic mask with a structured home programme. Your doctor will recommend the option that best suits your pigment, skin sensitivity and lifestyle.

What side effects should I expect?

Dryness, peeling, redness and mild stinging are common when you start. Strong irritation, swelling, blistering, marked darkening or skin thinning need medical review.

Ready for a personalised melasma plan?

Book your doctor consultation at Satini

We will assess your pigment, explain whether Kligman Solution is suitable and create a safe plan for your skin. If another treatment is more appropriate, we will tell you.

Medical information: This page provides general education and marketing information. It does not replace an individual medical assessment. Prescription treatment, formula strength, duration and combination therapy are decided by your treating doctor.